Abstract Introduction Though animal-related injuries and fatalities have been documented throughout the world, the variety of attacks by wild animals native to rural East Africa are less commonly described.Given the proximity of our northwestern Tanzania hospital to Lake Victoria, Lake Tanganyika, and the Serengeti National Park, and presentation o
Abstract The Food and Drug Administration (FDA) has approved vaccines designed by GSK, copyright LAUNDRY BASKET and Moderna to protect high-risk populations against respiratory syncytial virus (RSV).These vaccines employ the pre-fusion F (pre-F) protein as the immunogen.In this study, we explored an mRNA vaccine based on a modified pre-F protein ca
Poly(ADP-Ribose) polymerases (PARPs) are enzymes that metabolize NAD+.PARP1 and PARP10 were previously implicated in the regulation of autophagy.Here we showed that cytosolic electron-dense particles appear in the cytoplasm of C2C12 myoblasts in which PARP2 is silenced by shRNA.The cytosolic electron-dense bodies resemble autophagic vesicles and, i